Arbitrary mail headers can be set by using the addHeader() method. It requires two parameters containing the name and the value of the header field. A third optional parameter determines if the header should have only one or multiple values: addHeader('X-MailGenerator', 'MyCoolApplication'); $mail->addHeader('X-greetingsTo', 'Mom', true); // multiple values $mail->addHeader('X-greetingsTo', 'Dad', true); ]]> To set the Reply-To: header there exists the function setReplyTo($email, $name=null), because it requires additional special escaping of the different parts (email and name).